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产品名称:BD human CD16流式抗体PE-CY7标记

产品型号:557744

产品报价:12

产品特点:BD human CD16流式抗体PE-CY7标记
宿主:mouse
反应物种:human
规格:100T
应用:流式
供应商:上海力敏实业有限公司

557744BD human CD16流式抗体PE-CY7标记的详细资料:

BD human CD16流式抗体PE-CY7标记BD human CD16流式抗体PE-CY7标记

英文名:PE-Cy™7 Mouse Anti-Human CD16

克隆号:Clone  3G8  (RUO)

Brand

BD Pharmingen™

Vol. Per Test

5 µl

Isotype

Mouse BALB/c x DBA/2, also known as CD2F1 or CDF1 IgG1, κ

Reactivity

Human (QC Testing)  Rhesus, Cynomolgus, Baboon (Reported) 

Application

Flow cytometry (Routinely Tested) 

Immunogen

Human polymorphonuclear leukocytes

Workshop No.

IV N409

Entrez Gene ID

2214  2215 

Storage Buffer

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Regulatory Status

RUO

 

规格

 100 Tests 25 Tests 

货号

557744

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DESCRIPTION

 

The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes. The 3G8 antibody is reported (Vossebeld et al., 1997) to increase intracellular calcium levels in human neutrophils by interacting with bothFcγRIIa and FcγRIIIb molecules. This antibody has also been reported to induce homotypic neutrophil aggregation.

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