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产品名称:Peprotech Recombinant Human FGF-basicpe重组人FGF-basicpe细胞生长因子

产品型号:AF-100-18B

产品报价:

产品特点:Peprotech Recombinant Human FGF-basicpe详细产品信息请

AF-100-18BPeprotech Recombinant Human FGF-basicpe重组人FGF-basicpe细胞生长因子的详细资料:

 

Recombinant Human FGF-basic (154 a.a.)

Catalog Number:
AF-100-18B
Synonyms:
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
Description:
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.Manufactured using all non-animal reagents.
AA Sequence:
AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
Source:
E.coli
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5ng/ml corresponding to a specific activity of ≥ 2 x 106units/mg. 

Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
 
 
 
 
Cross Reactivity:
Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken, Human, Chicken, Horse, N/A
Research Interests:
Angiogenesis/ Cardiovascular Angiogenesis/ Cardiovascular Cell Culture Cell Culture
FGF Superfamily FGF Superfamily Inflammation Inflammation
Neurobiology Neurobiology Proliferation Proliferation
Stem Cells & Differentiation Stem Cells & Differentiation Wound Healing Wound Healing
 
 
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.
 

 

 

 

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