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产品名称:peprotech Recombinant Murine IFN-γ细胞因子

产品型号:peprotech 315-05

产品报价:

产品特点:Synonyms:

Immune Interferon, type II interferon, T cell interferon, MAF

此类产品还有重组人的IFN

peprotech 315-05peprotech Recombinant Murine IFN-γ细胞因子的详细资料:

Catalog Number:

315-05
Synonyms:
Immune Interferon, type II interferon, T cell interferon, MAF
Description:
IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.
AA Sequence:
MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
 
 
 
 
Cross Reactivity:
Rabbit, Rat, Mouse, Mouse + Chicken, Human, Cow, Bacteria, N/A, Mouse + Parasite
Research Interests:
AIDS /  HIV AIDS / HIV Angiogenesis/ Cardiovascular Angiogenesis/ Cardiovascular
Cancer Cancer Diabetes /  Weight Regulation Diabetes / Weight Regulation
Immune System Immune System Neurobiology Neurobiology
Stem Cells & Differentiation Stem Cells & Differentiation Allergy Allergy
Transplantation Transplantation  

 

 

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